Primary Care for HIV-Infected Patients in Resource-Limited Settings

  • Authors: Charles van der Horst, MD; F. Parker Hudson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/4/18 (What's New)

Summary

  • WHO recommends HIV-1 RNA monitoring every 6-12 months in patients receiving ART (Management Guidelines)[WHO ART]
    • HIV-1 RNA > 1000 copies/mL on 2 separate occasions within a 3-month interval with adherence support between measurements after ≥ 6 months on ART is confirmation of treatment failure
    • In settings with limited access to viral load testing, a targeted viral load strategy to confirm suspected treatment failure based on immunologic or clinical criteria should be used to avoid unnecessary switching to second-line ART regimens

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