inPractice® - Treatment Complications

Special Considerations in the Management of Women With HIV, Including Management of Conception and Pregnancy

Author: Kristine Patterson, MD (More Info)
Section Editor: Judith S. Currier, MD, MSc
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 7/5/18 (What's New)

Summary

Antiretroviral-associated adverse events are more frequent in women than men^{[Prins 2005; Molina 2010; Mills 2009; Brinkman 1999; Bersoff-Matcha 2001; Mazhude 2002; Sanne 2005]} and women may be more likely to modify or discontinue ART because of adverse events^{[Lucas 1999]}
Initiation of a nevirapine-containing regimen should be avoided in women with a CD4+ cell count > 250 cells/mm³ due to increased risk for severe hepatotoxicity^{[Hitti 2004]}

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Keywords: Dermatologic Complications, Dyslipidemia, Endocrine Disorders, Fat Perturbations, Hepatic Complications, Initial Antiretroviral Therapy, Pharmacokinetics, Treatment Complications, Women