Non–AIDS-Defining Cancers

  • Authors: David Aboulafia, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/15/21 (What's New)


  • HCC diagnosis should be suspected in individuals with underlying liver disease who develop rising serum AFP
  • Persons with HIV with cirrhosis and HBV or HCV coinfection should be screened according to AASLD practice guidelines for the general population, with hepatic ultrasound and AFP measurement at 6-month intervals (Management Guidelines)[AASLD HCC]

  • Degree of cirrhosis should be assessed before definitive treatment using Child-Pugh classification

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