Agents Used in Antiretroviral Therapy
Summary
- Attachment inhibitors bind to gp120 and selectively inhibit the interaction between the virus and cellular CD4 receptors, which prevents viral entry into host cells
- Fostemsavir is currently the only approved agent in this class[FDA Fostemsavir] Fostemsavir
- Fostemsavir was approved in July 2020 for use in combination with other ARV agents in heavily treatment–experienced patients with multidrug-resistant HIV infection who are experiencing failure of their current ART regimen[FDA Fostemsavir]
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