Management of Treatment-Experienced HIV-Infected Patients

  • Author: Eric S. Daar, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 8/1/18 (What's New)


  • Raltegravir and elvitegravir resistance typically evolves over time, with initial patterns replaced over time by mutations conferring high level resistance if their use is continued[Fransen 2009]
  • Twice-daily doses of dolutegravir have been shown to be effective in these patients[Eron 2013]

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