Non–AIDS-Defining Cancers
Summary
- Current NCCN guidelines emphasize importance of smoking as risk factor for anal carcinoma[NCCN Anal] with risk increased ~ 8 times for smokers versus nonsmokers[Etienney 2008]
- Quadrivalent and 9-valent HPV vaccine indicated for prevention of anal cancer and associated precancerous lesions due to HPV types 6, 11, 16, and 18 (also 31, 33, 45, 52, and 58 for 9-valent vaccine) in people aged 9-26 years[FDA 2010a; FDA 2014]
- AIN may be treated with topical agents and/or surgery[Abbasakoor 2005; Stier 2013] or infrared coagulation for discrete high-grade anal-canal lesions[Stier 2008]
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Keywords: Cancer, Sexually Transmitted Diseases