Key Pharmacologic Principles and Drug-Drug Interactions in HIV Patient Care

  • Authors: Amanda H. Corbett, PharmD, BCPS, FCCP; Colin I. Sheffield, PharmD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 6/3/19 (What's New)


  • Approved antiretrovirals have varying potential for drug–drug interactions with other antiretrovirals and with concomitant medications
  • Comedication use is common in HIV-infected patients[Zhou 2014; Greene 2014; Robertson 2005]
  • Clinicians providing care to HIV-infected patients must be cognizant of the potential for drug–drug interactions

Action required