Hepatic Disease in HIV-Infected Patients
Summary
- Drug–drug interactions between HCV therapy and ART is the primary consideration when selecting DAA therapy in HCV/HIV-coinfected patients
- The AASLD/IDSA and EASL provide recommendations on the use of certain HCV therapies with ART (Table 12)
- Sofosbuvir is a substrate for P-gp and BCRP; should not be coadministered with potent P-gp inducers such as rifampin or St. John’s wort[FDA Sofosbuvir]
- Sofosbuvir is a substrate for P-gp and BCRP; should not be coadministered with potent P-gp inducers such as rifampin or St. John’s wort[FDA Sofosbuvir]
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