Management of Children With or Exposed to HIV

  • Authors: James A. McAuley, MD, MPH; Mariam Aziz, MD (More Info)
  • Associate Editor: Judith S. Currier, MD, MSc
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 7/12/18 (What's New)

Summary

  • Infants diagnosed with HIV infection while receiving antiretroviral prophylaxis for the prevention of mother-to-child transmission should stop prophylactic therapy and initiate fully active combination ART (Management Guidelines)[DHHS Pediatric]
  • More than 20 antiretrovirals have FDA approval for use in children; 16 are available as liquids or chewable tablets (Table 2)
  • DHHS and WHO guidelines recommend lopinavir/ritonavir plus 2 NRTIs as a preferred initial therapy for children 14 days of age or older to younger than 3 years of age[DHHS Pediatric; WHO ART]

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