Management of Children With or Exposed to HIV
Summary
- Treatment guidelines from the DHHS and WHO recommend initiating ART in all infants with HIV younger than 12 months of age, regardless of clinical status, CD4+ cell count, or HIV-1 RNA (Management Guidelines)[DHHS Pediatric] (Management Guidelines)[WHO ART]
- Early use of ART in perinatally infected infants improves clinical and immunologic outcomes[Violari 2008; Faye 2004; Luzuriaga 2000; Faye 2002; Aboulker 2004]
- Issues that might affect adherence should be discussed with caregivers and addressed before treatment initiation
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