Modifying Antiretroviral Therapy in Virologically Suppressed HIV-Infected Patients

  • Author: José R. Arribas, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 10/18/21 (What's New)


  • STRIIVING study demonstrated that switching from virologically suppressive regimen (2 NRTIs plus PI, NNRTI, or INSTI) to single-tablet, once-daily abacavir/dolutegravir/lamivudine was noninferior to continuing baseline ART for maintenance of virologic suppression at Week 24[Trottier 2017]
  • NEAT-022 study showed that switching virologically suppressed patients with high cardiovascular risk from their current regimen to dolutegravir-based ART was noninferior and improved lipid profiles[Gatell 2017; Gatell 2019]

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