Management of Children With or Exposed to HIV

  • Authors: James A. McAuley, MD, MPH; Mariam Aziz, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 9/5/21 (What's New)

Summary

  • Current DHHS guidelines recommend that 4-week neonatal zidovudine can be used in infants of mothers who received standard combination ART during pregnancy with continuous virologic suppression and no maternal adherence concerns (ie, at low risk of HIV transmission)[DHHS Perinatal]
    • Frequency of hematologic monitoring should be based on specific circumstances of each case[DHHS Perinatal]
    • If anemia or other hematologic abnormalities occur, the decision to stop or continue prophylaxis should be individualized, and consultation with a pediatric HIV infection expert is recommended[DHHS Perinatal]

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