inPractice® - HIV-Associated Nephropathy

Timing of Initiation of First-line Antiretroviral Therapy

Authors: Marshall J. Glesby, MD, PhD; Timothy J. Wilkin, MD, MPH (More Info)
Section Editor: Joel E. Gallant, MD, MPH
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 4/1/16 (What's New)

Summary

Uncontrolled HIV replication is a risk factor for HIVAN
ART is associated with preservation of renal function and prolonged survival in patients with HIVAN^{[Atta 2006; Schwartz 2005]}
DHHS (Management Guidelines)^{[DHHS ART]}and IDSA (Management Guidelines)^{[Lucas 2014]}treatment guidelines recommend ART initiation in patients with HIVAN

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Keywords: Cardiovascular Disease, Initial Antiretroviral Therapy, Pregnancy, Renal Complications, Special Populations, Viral Hepatitis Coinfection