inPractice® - Saquinavir

Agents Used in Antiretroviral Therapy

Authors: Philip Grant, MD (More Info)
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 7/19/21 (What's New)

Summary

Saquinavir is indicated in combination with ritonavir and other antiretroviral agents for treatment of HIV infection^{[FDA Saquinavir]}
It may be used in both treatment-naive and treatment-experienced patients
Saquinavir should always be dosed with ritonavir (1000 mg saquinavir plus 100 mg ritonavir twice daily) and taken within 2 hours of a meal

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Keywords: Initial Antiretroviral Therapy, Management of Treatment-Experienced Patients, Special Populations, Treatment Complications