Management of Neurologic Diseases

  • Authors: David M. Simpson, MD; Jessica Robinson-Papp, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • ART is the only treatment shown to significantly improve HAD in patients with untreated HIV[Sacktor 1999; Dore 2003; Sacktor 2001]
  • However, HAD and HAND may develop in patients who are receiving effective ART
  • It is not clear whether antiretroviral penetration of the blood-brain barrier significantly affects cognitive performance in HIV-infected patients[Cysique 2009; Marra 2009a]

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