HIV Testing and Diagnosis

  • Author: Peter Leone, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 1/9/18 (What's New)


  • Antibody testing is the gold-standard screening test for HIV infection
  • Current recommendations are that initial testing be performed with a fourth-generation immunoassay and for the results to be confirmed with an immunoassay that differentiates HIV-1 antibodies from HIV-2 antibodies (Figure 1) (Management Guidelines)[CDC HIV Testing]

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