Agents Used in Antiretroviral Therapy
Summary
- Integrase strand transfer inhibitors (INSTIs) act to inhibit strand transfer, a process catalyzed by HIV integrase enzyme
- FDA-approved INSTIs include bictegravir, dolutegravir, elvitegravir, and raltegravir (Table 7)
- INSTI regimens are among preferred regimens in US and European guidelines and are the only preferred regimens in US guidelines Dolutegravir
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