Management of Bone Disease and Body Composition Changes
Summary
- Compared with thymidine analogues stavudine[Gallant 2004] and zidovudine,[Gallant 2006] neither tenofovir DF nor abacavir promote lipoatrophy[Podzamczer 2007]
- No evidence of lipoatrophy with tenofovir AF
- Little evidence that NNRTIs, PIs, or integrase inhibitors significantly affect body composition, although some data support increased fat gain with boosted PI therapy[McComsey 2011a] Genetic Factors
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Keywords: Fat Perturbations, Treatment Complications