Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • Viral hepatitis may be caused by a broad range of pathogens (Table 1)
  • Hepatic injury may be mild, with only transient elevation in aminotransferases, or may lead to acute hepatitis or fulminant hepatic failure
  • The effects of these viral infections on immunocompromised hosts, including recipients of solid organ transplantations, deserve special attention

Human viral hepatitis results from a wide range of pathogens beyond the classic hepatotropic viruses, hepatitis A through E (Table 1). Secondary and exotic hepatotropic viruses may cause hepatic injury ranging from mild and transient elevation of aminotransferases to acute hepatitis and, occasionally, to fulminant hepatitis.

Table 1. Pathogens Known to Cause Human Viral Hepatitis


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Primary Hepatotropic Viruses

Secondary Hepatotropic Viruses

Exotic Hepatotropic Viruses