Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • CCHF is endemic to Africa, Asia, Eastern Europe, and the Middle East and is transmitted via tick bites, contact with a patient with CCHF during the acute stage of infection, or contact with infected livestock
  • Initial symptoms are nonspecific, including fever, myalgia, and headache, gradually progressing to hemorrhagic disease with a high fatality rate[Ergönül 2006a]
  • Hepatomegaly and splenomegaly have been reported to occur in up to one third of patients[Hoogstraal 1979]

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