Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)

Summary

  • Liver biopsy in patients with CMV often demonstrates mononuclear cell infiltration of the portal areas but may also reveal granulomatous inflammation or microabscesses[Ten Napel 1984]
  • Qualitative diagnostic assays, such as the CMV immunoglobulin M (IgM) test, can be falsely positive
  • Therefore, quantitative diagnostic assays for CMV are essential for diagnosis, including molecular assays (PCR and other amplification assays) and antigen-detection (pp65 antigenemia) assays (Management Guidelines)[Razonable 2013]

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