Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • Primary EBV infection in children typically is asymptomatic at seroconversion
  • Primary infection in adolescents and young adults typically presents as infectious mononucleosis (fever, sore throat, lymphadenopathy). Hepatic involvement is common in EBV infection and varies in severity
  • Rarely, patients will develop chronic active EBV infection, which has high morbidity and mortality related to hepatic failure, lymphoma, sepsis, or hemophagocytic syndrome[Drebber 2006; Petrova 2010]

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