Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • Clinical signs of HSV hepatitis include so-called anicteric hepatitis (low or normal bilirubin, severe transaminase elevations, fever, abdominal pain, and influenza-like symptoms). Approximately 50% of patients also have HSV-related mucocutaneous lesions[Norvell 2007; Kaufman 1997]
  • Three quarters of cases rapidly progress to acute liver failure, with mortality reaching almost 90%, often because of delayed diagnosis and lack of specific treatment[Norvell 2007]

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