Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • Empiric treatment with parenteral acyclovir is indicated for all patients presenting with acute liver failure of unknown etiology, until an alternative diagnosis is made or HSV is excluded[Norvell 2007; Sterling 2001]
  • Urgent liver transplantation is the only definitive therapy, but this is controversial and limited by high mortality.[Norvell 2007] Following liver transplantation, lifelong antiviral therapy is required to prevent recurrences

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