Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • Complications of VZV infection are rare in immunocompetent patients, although elevated levels of aminotransferases without hepatic symptoms are seen in up to one third of cases[Bovill 1998; Borum 1996]
  • Cases of VZV hepatitis with acute liver failure occur rarely in patients who are immunocompromised due to splenectomy, solid organ or bone marrow transplantation, use of corticosteroids, or HIV infection[Patti 1990; Dits 1998; Hirose 2006; Pishvaian 2006; Roque-Afonso 2008; Verleden 2012]
  • Abdominal pain is the most common symptom, in conjunction with profoundly elevated aminotransferases or pancreatic enzymes[David 1998]

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