Other Viruses That Affect the Liver

  • Authors: Lisa VanWagner, MD, MSc, FAST (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 9/4/18 (What's New)


  • Standard treatment for VZV hepatitis is intravenous acyclovir which should be started immediately upon suspicion of the diagnosis as mortality associated with VZV-induced hepatic failure is very high[Breuer 2007]
  • Varicella zoster immune globulin might modify the clinical course of VZV infection only if administered within 72 hours following exposure[Springfield 2009]
  • Most treatment failures are due to host immunodeficiency rather than drug resistance to acyclovir

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