Virology and Immunology of Hepatitis Viruses

  • Authors: Esperance Anne Kreek Schaefer, MD, MPH; Raymond T. Chung, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/10/18 (What's New)


  • 8 major genotypes of HDV vary in geographic distribution and clinical outcomes
    • More than 1 genotype may be present in a single individual but 1 genotype will dominate[Wu 1999]
    • Genotype 1 is associated with more severe disease, faster progression, and reduced treatment response[Su 2006; Yurdaydin 2010; Calle Serrano 2012]

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