Virology and Immunology of Hepatitis Viruses

  • Authors: Esperance Anne Kreek Schaefer, MD, MPH; Raymond T. Chung, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/10/18 (What's New)


  • HCV is a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family
  • 10 viral proteins (both structural and nonstructural) are encoded by a long ORF (Figure 3)
  • Several cell surface receptors have been identified as involved in binding and entry of the virus (Figure 4)[Mazumdar 2011]

Action required