Virology and Immunology of Hepatitis Viruses

  • Authors: Esperance Anne Kreek Schaefer, MD, MPH; Raymond T. Chung, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/10/18 (What's New)


  • Early immunologic response to HCV infection is a classic type I interferon response
  • After acute infection, there is a rapid induction of ISGs
    • Despite induction of antiviral type I interferon response, viral levels continue to rise after infection[Boonstra 2008]

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