Hepatitis A Virus and Hepatitis E Virus: Different Viruses With Similar Stories

  • Author: Kenneth E. Sherman, MD, PhD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 5/17/18 (What's New)


  • Two HAV monovaccines are approved for individuals at least 12 months of age and are highly effective when given as a 2-dose series of intramuscular injections[FDA Hepatitis A Vaccine; FDA Hepatitis A Vaccine, Inactivated]

  • The US Advisory Committee on Immunization Practices recommends routine HAV vaccination for children, travelers to endemic areas, MSM, users of illicit drugs, families of adoptees from intermediate- or high-endemicity countries, researchers working with HAV, individuals with chronic liver disease, individuals with clotting-factor disorders, and those with direct contact with HAV-infected individuals[CDC HAV FAQ]

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