Hepatitis B Epidemiology, Pathogenesis, Diagnosis, and Natural History

  • Author: Marc G. Ghany, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/2/18 (What's New)


  • 10 different genotypes of HBV have been recognized and are designated by letters A-J
  • HBV genotypes differ among different geographic regions (Table 2)
  • Migration is changing the pattern of genotype distribution, particularly in the US, with an increase in genotypes from countries with a high prevalence of HBV infection (predominantly HBV genotypes B and C)[Chu 2003]

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