Hepatitis B Epidemiology, Pathogenesis, Diagnosis, and Natural History

  • Author: Marc G. Ghany, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/2/18 (What's New)


  • Sexual transmission is the major route of HBV transmission in the US and Western Europe
  • Sexual transmission accounts for approximately 38% of acute HBV infections in the US; 25% are estimated to occur via sex between men[Wasley 2008]
  • Risk of sexual transmission is related to number of lifetime sexual partners, the lack of protection used during sexual encounters, and a history of sexually transmitted infection[Schillie 2018a]

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