Hepatitis B Epidemiology, Pathogenesis, Diagnosis, and Natural History

  • Author: Marc G. Ghany, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/2/18 (What's New)


  • Guidelines for postexposure prophylaxis for adults with occupational (Management Guidelines)[CDC HCP HBV Prevention] and nonoccupational[Schillie 2018a] exposures to HBV are available
  • Postexposure prophylaxis is recommended for anyone who is exposed to HBV and is considered susceptible to HBV infection
    • The interval for effectiveness of prophylaxis is unlikely to exceed 1 week for individuals exposed percutaneously or 2 weeks for sexual exposures[Schillie 2018a]

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