Hepatitis B Epidemiology, Pathogenesis, Diagnosis, and Natural History

  • Author: Marc G. Ghany, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/2/18 (What's New)

Summary

  • Approximately 5% to 15% of healthy individuals fail to respond to the 3-dose HBV vaccine series[CDC 1991]
  • People with anti-HBs levels < 10 mIU/mL following the primary HBV vaccine series should be revaccinated with 3 doses according to the appropriate schedule and retested after the third dose (Table 4)
  • Individuals with anti-HBs levels < 10 mIU/mL following revaccination should be tested for HBsAg

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