Management of Hepatitis B Infection
- Chronic HBV infection affects an estimated 257 million people globally
- Most cases in southeast Asia and sub-Saharan Africa[WHO HBV]
- Without treatment, HBV may progress over time to liver disease, fibrosis, and cirrhosis, leading to hepatocellular carcinoma and death
- Successful anti-HBV therapy reduces disease progression
- International guidelines recommend anti-HBV treatment in patients with persistent necroinflammation and viral replication
- Nucleos(t)ide analogues or peginterferon are recommended first-line therapy options
Chronic hepatitis B virus (HBV) infection affects an estimated 257 million people globally, with the majority of infected patients residing in southeast Asia and sub-Saharan Africa.[WHO HBV]...