Management of Hepatitis B Infection

  • Authors: Harry L. A. Janssen, MD, PhD; Milan J. Sonneveld, MD, PhD, MSc (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 5/25/18 (What's New)


  • Complete eradication of HBV cannot be achieved with current therapies
  • The main goal of treatment is to halt progression of liver inflammation to fibrosis, cirrhosis, or hepatocellular carcinoma
  • Undetectable HBV DNA, both spontaneous and treatment induced, and clearance of HBeAg and HBsAg, are associated with a lower risk of cirrhosis, hepatocellular carcinoma, and death[Iloeje 2006; Chen 2006; Yang 2002]

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