Management of Hepatitis B Infection

  • Authors: Harry L. A. Janssen, MD, PhD; Milan J. Sonneveld, MD, PhD, MSc (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 5/25/18 (What's New)


  • Baseline predictors of response to peginterferon in HBeAg-negative patients include female sex, HBV genotype, higher baseline ALT level, and lower baseline HBV DNA levels[Bonino 2007]
  • Nucleos(t)ide analogue–based treatment is the best choice for most patients with HBeAg-negative disease

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