Hepatitis B Management in Special Populations

  • Author: Alessandra Mangia, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 6/4/18 (What's New)


  • Patients with HBV who are viremic at the time of transplantation have a higher rate of recurrence posttransplantation[Samuel 2007]
  • Antiviral therapy given before transplant aims to reduce serum HBV DNA to low or undetectable levels. This may delay or even prevent the need for transplantation
    • Tenofovir DF and entecavir are recommended for use in HBsAg-positive patients undergoing liver transplantation for end-stage liver disease or hepatocellular carcinoma[EASL HBV]

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