Hepatitis Delta Virus

  • Author: Mario Rizzetto, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 6/1/18 (What's New)


  • HDV is a unique RNA pathogen that replicates through a double rolling circle mechanism unknown in other animal viruses
  • HDV is dependent on HBV for infection and can thrive only in patients with HBsAg
    • The only function of HBV required from HDV is the HBsAg coat for morphogenesis

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