Hepatitis Delta Virus

  • Author: Mario Rizzetto, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 6/1/18 (What's New)

Summary

  • Individuals with HDV and signs of active replication should be considered for treatment regardless of HIV coinfection due to the poor prognosis of HDV
  • No data available on efficacy of peginterferon in HDV/HIV-infected patients, but relatively poor efficacy and high toxicity has been observed in HBV/HIV-coinfected patients
  • Therefore, HBV/HDV/HIV-coinfected patients should only be treated if the benefits of peginterferon therapy are judged to outweigh the risks of liver-related complications

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