Management of Hepatitis C Infection

  • Authors: Jordan J. Feld, MD, MPH; Hemant Shah, MD, MScCH HPTE (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/24/18 (What's New)

Summary

  • On-treatment virologic response is predictive of SVR with older DAA regimens
    • Undetectable HCV RNA at Week 4 (RVR) is a positive predictor of SVR with boceprevir or telaprevir + peginterferon[Poordad 2011; Jacobson 2011a]
    • Detectable HCV RNA at Week 12 is a negative predictor of SVR to boceprevir or telaprevir + peginterferon[Poordad 2011; Jacobson 2011a]

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