Management of Hepatitis C Infection

  • Authors: Jordan J. Feld, MD, MPH; Hemant Shah, MD, MScCH HPTE (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/24/18 (What's New)


  • Current HCV therapies target viral proteins involved in HCV replication and assembly such as the NS3/NS4A protease, NS5B RNA–dependent RNA polymerase, and the NS5A replication complex component
  • Combination therapies employ multiple DAAs that target different stages of the HCV life cycle simultaneously

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