Management of Hepatitis C Infection
Summary
- Treatment-naive patients with compensated cirrhosis should be treated in the same manner as patients without cirrhosis, although regimens and treatment duration differ (Management Guidelines)[AASLD-IDSA HCV]
- Antiviral treatment in patients with cirrhosis is associated with increased risk of complications and lower rates of SVR when compared with patients without cirrhosis using peginterferon-containing regimens[Iacobellis 2007]
- Combination therapy with ledipasvir/sofosbuvir, daclatasvir plus sofosbuvir, or sofosbuvir/velpatasvir may be considered in patients with compensated cirrhosis awaiting liver transplantation or those with recurrent HCV after liver transplantation[AASLD-IDSA HCV]
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