Management of Hepatitis C Infection

  • Authors: Jordan J. Feld, MD, MPH; Hemant Shah, MD, MScCH HPTE (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 1/9/21 (What's New)


  • Resistance associated variants have been identified for all DAAs
  • Resistance emerges rapidly with use of DAA monotherapy
  • Cross-resistance occurs within DAA classes
  • Mechanisms of Resistance
      Resistance Associated Variants: Persistence After Treatment Discontinuation and Implications for Retreatment

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