Management of Hepatitis C Infection
Summary
- Viral and host factors influence likelihood of response to interferon-based therapy (Table 35) (Table 36)[Sarrazin 2010] Viral Factors
- Subgenotype 1a has lower barrier to resistance to protease and NS5A inhibitors than subgenotype 1b[Halfon 2011]
- Presence of NS5A RAVs at baseline in patients with genotype 1a HCV infection lowers SVR rate for elbasvir/grazoprevir, necessitating longer duration therapy and/or addition of ribavirin
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Keywords: Hepatitis C-Treatment