Management of Hepatitis C Infection

  • Authors: Jordan J. Feld, MD, MPH; Hemant Shah, MD, MScCH HPTE (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 7/24/18 (What's New)


  • Viral and host factors influence likelihood of response to interferon-based therapy (Table 40) (Table 41)[Sarrazin 2010]
  • Viral Factors
    • Responses to approved interferon-based therapies are greatest with genotype 2, followed by genotype 3, genotype 4, and then genotype 1
    • High baseline HCV RNA is associated with poorer response to interferon-based therapies
    Host Factors

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