Management of Hepatitis C Infection
Summary
- Advanced fibrosis/cirrhosis is associated with reduced likelihood of SVR, including to DAA therapy
- IL28B genotype is associated with interferon responsiveness and SVR to interferon-based therapy[Ge 2009; Tanaka 2009; Thomas 2009]
- Patients with favorable CC genotype have high rates of SVR to peginterferon/ribavirin dual therapy; incremental benefit with PI-based therapy, although many such patients will qualify for shortened PI therapy[Jacobson 2011b; Poordad 2012]
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Keywords: Hepatitis C-Prognosis, Hepatitis C-Treatment