Introduction

• HCV is a major cause of cirrhosis and hepatocellular carcinoma worldwide^{[Ponziani 2011]}
• In the US, HCV is a leading cause of liver-related death and the most common indication for liver transplantation^{[Fayek 2016; CDC HCV FAQ]}
• Effective HCV therapies are available; the presence of comorbidities, coinfections, and other special patient circumstances may complicate their use in clinical practice

HCV is a leading cause of cirrhosis and hepatocellular carcinoma across the globe.^{[Ponziani 2011]} With an estimated 71 million people chronically infected worldwide and approximately 399,000 HCV-related deaths each year,^{[WHO HCV]...}