Hepatitis C Management in Special Populations

  • Author: Mark S. Sulkowski, MD (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 8/17/18 (What's New)

Summary

  • Clearance of HCV infection has been reported in approximately 25% to 40% of children with perinatal acquisition by 2 years of age, with up to another 12% clearing HCV infection before adulthood[Squires 2017]
    • Clearance may be associated with non–genotype-1 infection and IL28B CC genotype[Howell 2012]
  • Progression of liver fibrosis in children with HCV is minimal, and cirrhosis is uncommon[Bortolotti 2008; Iorio 2005; Jara 2003; Goodman 2008]

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