Management of Hepatitis C Infection

  • Authors: Jordan J. Feld, MD, MPH; Hemant Shah, MD, MScCH HPTE (More Info)
  • Editor In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 1/9/21 (What's New)


  • The risk of HCV reinfection is elevated among persons who inject drugs (PWIDs), HIV-coinfected men who have sex with (MSM), and individuals in correctional settings[Simmons 2016]
  • Long-term follow-up is advised for individuals achieving SVR yet remaining at an increased risk of reinfection
    • AASLD/IDSA guidelines recommend annual HCV RNA testing among individuals with ongoing risk factors for HCV infection (ie, PWID and HIV-coinfected MSM engaging in unprotected sex)[AASLD-IDSA HCV]

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