Hepatitis C Virus Epidemiology, Pathogenesis, Diagnosis, and Natural History

  • Author: Francesco Negro, MD (More Info)
  • Editors In Chief: Stefan Zeuzem, MD
  • Last Reviewed: 10/30/20 (What's New)


  • HCV seroprevalence is estimated at 17.4% among male and female state prisoners in the United States[Varan 2014]
    • High prevalence attributed to high-risk behaviors such as IDU and tattooing with nonsterile equipment[Imperial 2010; Vescio 2008]
    • Individuals with HCV infection are also more likely to interact with prison systems: approximately 750,000 HCV-infected individuals—1 out of 5 of the population with HCV infection—spend some time in correctional facilities each year[Altice 2017]

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